Nitric oxide and blood pressure

Q: I have been told that nitric oxide is helpful in controlling high BP and that l-arginine in combination with l-citrulline generates this in the blood. Have you heard anything on this?

A: What you have heard is true. Nitric oxide is a mediator for many functions within the body. The pathway is complex and can include the aminoacids you mention. For example, the well known impotence drug Viagra was developed because of the role nitric oxide plays in dilating the penile vascular system. Keep in mind, the use of any “supplement” in medicine is controversial. Recommended amounts of these amino acids are contained in a balanced, healthy diet.